{"id":24,"date":"2021-05-06T10:00:56","date_gmt":"2021-05-06T10:00:56","guid":{"rendered":"http:\/\/rettstudy.com\/?page_id=24"},"modified":"2025-04-17T18:39:14","modified_gmt":"2025-04-17T18:39:14","slug":"home","status":"publish","type":"page","link":"https:\/\/rettstudy.com\/","title":{"rendered":"Home"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.4.5″ custom_padding=”25px||25px||true|false”][et_pb_row _builder_version=”4.4.5″ background_color=”#f0f0f0″][et_pb_column type=”4_4″ _builder_version=”4.4.5″][et_pb_text _builder_version=”4.4.5″ header_font=”Lora||||||||” header_text_align=”center” header_text_color=”#666″]<\/p>\n

The Rett-002 study is now open for enrollment!<\/h1>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjgifX0=@” button_text=”Click here to register your interest” button_alignment=”center” _builder_version=”4.4.5″ _dynamic_attributes=”button_url” custom_button=”on” button_text_size=”14px” button_text_color=”#5aa1e3″ button_border_width=”2px” button_border_color=”#5aa1e3″ button_border_radius=”1px” button_font=”Source Sans Pro||||||||” custom_padding=”10px|22px|10px|22px|true|true” button_text_color_last_edited=”off|desktop” button_text_color__hover_enabled=”on|hover” button_text_color__hover=”#FFFFFF” button_bg_color__hover_enabled=”on|hover” button_bg_color__hover=”#5aa1e3″ button_bg_enable_color__hover=”on”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ fullwidth=”on” _builder_version=”4.4.5″][et_pb_fullwidth_slider _builder_version=”4.4.5″ custom_padding=”222px||222px||true|” auto=”on” auto_speed=”4500″ auto_ignore_hover=”on”][et_pb_slide _builder_version=”4.4.5″ background_enable_color=”off” background_image=”https:\/\/rettstudy.com\/wp-content\/uploads\/2021\/05\/1.jpg” background_enable_image=”on”][\/et_pb_slide][et_pb_slide _builder_version=”4.4.5″ background_enable_color=”off” background_image=”https:\/\/rettstudy.com\/wp-content\/uploads\/2021\/05\/2.jpg” background_enable_image=”on”][\/et_pb_slide][et_pb_slide _builder_version=”4.4.5″ background_enable_color=”off” background_image=”https:\/\/rettstudy.com\/wp-content\/uploads\/2021\/05\/3.jpg” background_enable_image=”on”][\/et_pb_slide][et_pb_slide _builder_version=”4.4.5″ background_enable_color=”off” background_image=”https:\/\/rettstudy.com\/wp-content\/uploads\/2021\/05\/4.jpg” background_enable_image=”on”][\/et_pb_slide][et_pb_slide _builder_version=”4.4.5″ background_enable_color=”off” background_image=”https:\/\/rettstudy.com\/wp-content\/uploads\/2021\/05\/5.jpg” background_enable_image=”on”][\/et_pb_slide][\/et_pb_fullwidth_slider][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.4.5″ custom_padding=”28px||13px|||”][et_pb_row _builder_version=”4.4.5″][et_pb_column type=”4_4″ _builder_version=”4.4.5″][et_pb_text _builder_version=”4.4.5″ text_font=”Source Sans Pro|300|||||||” text_text_color=”#343e47″ text_font_size=”17px” text_line_height=”27px” header_font=”Lora|700|on||||||” header_text_color=”#222222″ header_font_size=”28px” header_line_height=”36px”]<\/p>\n

<\/h1>\n

Does someone you know have Rett Syndrome?<\/h1>\n

If so, they may be eligible to participate in a research study on a new investigational medication for children and adolescent females aged 5-15 with Rett syndrome.<\/p>\n

Rett syndrome is a genetically determined neurological disorder, which is characterized by arrested development, regression of acquired skills, loss of purposeful use of the hands and speech, stereotypical movements, and intellectual disability.<\/p>\n

Currently, treatment for Rett syndrome focuses on the management of specific symptoms and supportive care.<\/p>\n

 <\/p>\n

What is the purpose of the Rett study?<\/h1>\n

This study investigates a novel oral medication called \u201ctrofinetide\u201d (also known as NNZ-2566), which has a unique way of acting relative to other drugs that are being tested for Rett syndrome.<\/p>\n

The purpose of the study is to look at the safety and tolerability of trofinetide in children and adolescents with Rett syndrome. The study will also investigate the effectiveness of trofinetide during treatment.<\/p>\n

 <\/p>\n

What are the specifics of the medication?<\/h1>\n

This study investigates trofinetide, a modified version of a biologically active part of Insulin-like Growth Factor (IGF-1). IGF-1 is a protein in the human body that helps cells grow. Trofinetide is a modified version of a small part of IGF-1 called GPE, which detaches from IGF-1 in the brain. IGF-1 and GPE play a significant role in regulating the development of the brain and maintaining healthy brain function.<\/p>\n

Trofinetide may help to improve brain function by reducing inflammation, regulating the functioning of cells called microglia, normalising the connections between brain cells and restoring depressed levels of IGF-1 in the brain.<\/p>\n

Click on the image or the link below to access a video about the science of trofinetide;<\/p>\n

www.neurenpharma.com\/IRM\/content\/default.aspx<\/a><\/p>\n

 <\/p>\n

How Does Physical Therapy Come Into Play?<\/h1>\n

Physical therapy is also crucial for the treatment of Rett Syndrome symptoms.\u00a0<\/p>\n

For more information on the latest advancements in Physical Therapy for\u00a0Rett Syndrome,<\/p>\n

visit\u00a0physicaltherapycoralsprings.com<\/a><\/span><\/p>\n

 <\/p>\n

[\/et_pb_text][et_pb_image src=”https:\/\/rettstudy.com\/wp-content\/uploads\/2021\/05\/link-to-video-image-300×139-1.jpg” title_text=”link-to-video-image-300×139″ align=”right” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.4.5″ hover_enabled=”0″ positioning=”relative” position_origin_r=”top_right” vertical_offset=”-379px”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.4.5″][et_pb_column type=”1_2″ _builder_version=”4.4.5″][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.4.5″][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.4.5″ custom_padding=”25px||25px||true|false”][et_pb_row _builder_version=”4.4.5″ background_color=”#f0f0f0″][et_pb_column type=”4_4″ _builder_version=”4.4.5″][et_pb_text _builder_version=”4.4.5″ header_font=”Lora||||||||” header_text_align=”center” header_text_color=”#666″] The Rett-002 study is now open for enrollment! [\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjgifX0=@” button_text=”Click here to register your interest” button_alignment=”center” _builder_version=”4.4.5″ _dynamic_attributes=”button_url” custom_button=”on” button_text_size=”14px” button_text_color=”#5aa1e3″ button_border_width=”2px” button_border_color=”#5aa1e3″ button_border_radius=”1px” button_font=”Source Sans Pro||||||||” custom_padding=”10px|22px|10px|22px|true|true” button_text_color_last_edited=”off|desktop” button_text_color__hover_enabled=”on|hover” button_text_color__hover=”#FFFFFF” button_bg_color__hover_enabled=”on|hover” button_bg_color__hover=”#5aa1e3″ button_bg_enable_color__hover=”on”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ fullwidth=”on” _builder_version=”4.4.5″][et_pb_fullwidth_slider _builder_version=”4.4.5″ custom_padding=”222px||222px||true|” auto=”on” auto_speed=”4500″ auto_ignore_hover=”on”][et_pb_slide […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":""},"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t